Introduction to System Suitability for Gas Chromatography

As part of that sequence, we perform additional injections which allow us to verify that the entire GC system is working correctly, this is system suitability. The actual parameters assessed during system suitability vary between companies, the type of analysis we are performing, and the method/compounds being used. This module outlines some of the common system suitability tests we see in GC analyses.

Topics include:

• System precision
• Retention time check
• Chromatographic profile
• Sensitivity check
• Resolution check
• Recovery check (quality control)
• Standard verification
• Calibration verification
• Peak shape verification